Antibacterial surface functionalization of biomedical scaffolds: A transformation towards more adaptive, resilient regenerative therapy
Introduction The field of regenerative medicine has witnessed significant advancements with the introduction of biomedical scaffolds designed to facilitate tissue repair and regeneration. However, one of the most persistent challenges in scaffold-based therapies is the risk of bacterial infections. Such infections can lead to implant failure, delayed healing, and other complications. To overcome this issue, researchers are exploring antibacterial surface functionalization as a powerful solution. By integrating antibacterial agents or modifying scaffold surfaces, these advanced materials can actively prevent or combat infections, enhancing the effectiveness and resilience of regenerative therapies. Understanding Biomedical Scaffolds and Their Role in Regenerative Therapy Biomedical scaffolds are three-dimensional (3D) structures engineered to support cell growth, differentiation, and tissue regeneration. They act as temporary frameworks that promote the formation of new tiss...